The Effects of Exercise on Immunity

Key Points Exercise improves health and immunityOvertraining can reduce immunity though and make us more prone to infectionsIt is also important to take in enough total energy (‘fuel’) to preserve and improve immune function along with exercise It is widely accepted that exercise improves health and is, by extension, a valuable contributor to proper immune functioning and resistance to infection. However, excessive exercise is a stressor that can dampen immune functions and as a result, over-training can lead to increased rates of infection with colds and flu-like viruses, a situation commonly seen in athletes. Over-exercise or over-stress from any cause is pro-inflammatory and over half of all sports injuries are also secondary to overuse.1 Markers of antioxidant status such as glutathione concentration and inflammatory markers such as interleukin 10 are affected by long periods of intense training.2 So, exercise helps to mitigate stress and fatigue and helps us to modulate inflammatory/immune and antioxidant pathways, BUT too much (over-reaching) can be just as detrimental as too little. Overreaching and over-training syndrome in athletes is depicted as a continuum, this is also likely to be the case for generalised ‘stress’. So, excessive exercise (or any other stressor) can be thought of as stress, leading to fatigue, leading to a greater incidence of infection (and burnout). Excessive exercise (or any other stressor) can be thought of as stress, leading to fatigue, leading to a greater incidence of infection Moderate amounts of exercise improve immune system functions and reduce the risk of infection. On…

The Brain and Nootropic Issue: The Carb-Appropriate Review

Issue 3 | Volume 2 | March 2020 In this issue: This month, Cliff looks at the evidence behind diet and lifestyle for reducing the risk of dementia and other neurodegenerative disorders and how you can boost brain-power right now. Also this month, research commentary on a recent systematic review and meta-analysis on carbohydrate intake and metabolic syndrome risk, along with short research ‘bites’ on evening primrose oil, saunas and detox, and the paleo-keto diet. Featured article How to Optimise Brain Health & Reduce the Risk of Age-Related Cognitive Decline Brain health now and impending cognitive decline are two of the most pressing health considerations for people nowadays. In this review, Cliff looks at lifestyle, diet, and supplement interventions to help keep your brain healthy. Read the article here Articles All About: Nootropics Nootropics are supplements that purport to boost your brain-power and improve your cognition and mental performance. There are a lot of claims but many of these supplements lack research-backing. Find out what the evidence says about the most common and most studied nootropics. Read the article here Research Commentary Mini-research-reviews on: Is Evening Primrose Oil Worth Taking? What is the Evidence Behind the Palaeolithic Ketogenic Diet? Do Saunas Aid Detoxification? Does the Amount of Carbohydrate in the Diet Affect Metabolic Syndrome Risk? Members can download this month’s full issue below: [ppp_patron_only level=”10″] CARR-March-2020Download [/ppp_patron_only]